Carolyn Stopera

cstopera
Rotation Labs
Torsten Falk, Ph.D.
Andrew Fuglevand, Ph.D.
Erika Eggers, Ph.D.

Dissertation

2024
Preclinical Evaluation of the Mechanism Underlying Ketamine Activity as a Treatment for Parkinson's Disease and L-DOPA-Induced Dyskinesia
Dissertation Advisor
Torsten Falk, Ph.D.

Research Summary

Investigating the use of ketamine as a novel pharmacological treatment for L-DOPA-induced dyskinesia and potential neuroprotective agent for Parkinson's disease. Dissecting the mechanism by which ketamine can exert acute anti-parkinsonian and long-term anti-dyskinetic effects. 

Publications

Bartlett, M.J.*, Stopera, C.J.*, Cowen, S.L., Sherman, S.J., Falk, T. Differential effects of statins on the anti-dyskinetic activity of sub-anesthetic ketamine. Submitted to Movement Disorders. August 2024. 

Stopera, C.J.*, Bartlett, M.J.*, Liu, C., Esqueda, A., Parmar, R., Heien, M.L., Sherman, S.J., Falk, T. Differential effects of opioid receptor antagonism on the anti-dyskinetic and anti-parkinsonian effects of sub-anesthetic ketamine treatment in a preclinical model. Neuropharmacology. June 2024.

Jordan, G.A., Vishwanath, A., Holguin, G., Bartlett, M.J., Tapia, A., Winter, G.M., Sexauer, M.R., Stopera, C.J., Falk, T., Cowen, S.L. Automated system for training and assessing reaching and grasping behaviors in rodents. Journal of Neuroscience Methods. October 2023.

Melachuri, S.R., Stopera, C., Melachuri, M.K., Anetakis, K., Crammond, D.J., Castellano, J., Balzer, J.R., Thirumala, P.D. The efficacy of somatosensory evoked potentials in evaluating new neurological deficits after spinal thoracic fusion and decompression. Journal of Neurosurgery: Spine. March 2020.

*Denotes co-authorship.

Degree(s)

  • B.S. Neuroscience, Minor Chemistry - University of Pittsburgh
  • Certificate in Conceptual Foundations of Medicine

Minor(s)

Medical Pharmacology

Research Interests

Neurodegeneration, Pharmacology, Parkinson's Disease, Ketamine

Categories

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