Carolyn Stopera

Research Summary

Investigating the use of ketamine as a novel pharmacological treatment for L-DOPA-induced dyskinesia and neuroprotective agent for dopamine neurons in Parkinson's disease. Dissecting the mechanism by which ketamine can exert acute anti-parkinsonian and long-term anti-dyskinetic effects. 

Publications

Stopera, C.J., Bartlett, M.J., Liu, C., Esqueda, A., Parmar, R., Heien, M.L., Sherman, S.J., Falk, T., 2024. Differential effects of opioid receptor antagonism on the anti-dyskinetic and anti-parkinsonian effects of sub-anesthetic ketamine treatment in a preclinical model. Neuropharmacology. June 2024.

Jordan, G.A., Vishwanath, A., Holguin, G., Bartlett, M.J., Tapia, A., Winter, G.M., Sexauer, M.R., Stopera, C.J., Falk, T., Cowen, S.L. Automated system for training and assessing reaching and grasping behaviors in rodents. Journal of Neuroscience Methods. October 2023.

Melachuri, S.R., Stopera, C., Melachuri, M.K., Anetakis, K., Crammond, D.J., Castellano, J., Balzer, J.R., Thirumala, P.D. The efficacy of somatosensory evoked potentials in evaluating new neurological deficits after spinal thoracic fusion and decompression. Journal of Neurosurgery: Spine. March 2020.